Genome “Hotspots” of DNA Change Directly Correlated With Developmental Disability

 Collaboration between Penn State, University of California Davis/MIND Institute, and the University of Washington gained strides towards early detection and prevention with the identification of increased genetic change in concentrated areas of the genome that influence DNA structure in children with Autistic Spectrum Disorders. The study weighs the nature versus nurture debates among current autism research. Conducted under the umbrella of the CHARGE study, sponsored by the National Institute of Environmental Health Sciences, the research findings support the argument that genetics outweigh environment. Springing from previous research revealing rare DNA deletions or duplications among up to 10 percent of those with autism, this study found that more common DNA are also being duplicated excessively in the genome of autistic children creating concentrated areas of rapid change. Further, these researchers found that those children with the greatest DNA duplication throughout their genome had more difficulty with daily living skills, suggesting a direct correlation between this excessive DNA growth and developmental disability and shedding light on the discrepancies within the Autism Spectrum Disorders. Dr. Selleck of Penn State explains the findings in an article for Medical News Today saying, “the increased levels of both rare and common variants suggests the possibility that these individuals are predisposed to genetic alteration.” The research will be published in the journal Human Molecular Genetics.




For more information, visit:

“Link Between Autism And Increased Genetic Change in Regions Of Genome Instability.” Medical News Today. N.p., 4 Apr. 2013. Web. 4 Apr. 2013. <>.

This entry was posted in Autism America, Autism Causes, Autism News, Autism News, Autism Research and tagged , , , , , , . Bookmark the permalink. Post a comment or leave a trackback: Trackback URL.


  1. Posted April 5, 2013 at 2:30 pm | Permalink

    Hello that post was simpley awesome gratitude for those insights!

  2. Posted April 7, 2013 at 1:40 pm | Permalink

    I always spent my half an hour to read this webpage’s articles or reviews every day along with a cup of

Post a Comment

Your email is never published nor shared.

You may use these HTML tags and attributes <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>