Drug Treatment Corrects Autism Symptoms

Autism spectrum disorders (ASDs) are characterized by abnormalities in language and social behavior development. A new study stemming from a study done by researchers at the University of California, San Diego School of Medicine indicates that a majority of causes for autism are caused by a sustained cell danger response.

This suggests that autism happens when cells get fastened in a defensive metabolic mode and fail to communicate together, which can interfere with brain function and development. This theory was tested using a class of drugs that have been around for almost a century, to block the danger signal in a mouse model. They called this new treatment APT or antipurinergic therapy. A well known inhibitor, Suramin, most commonly used in African sleeping sickness treatment was tested. They found that in the mice model the drug restored 17 types of multi-symptom abnormalities, even after onset of symptoms.

The conclusions of this research, has given hope to an opportunity to develop a new class of anti-inflammatory drugs to treat autism spectrum disorders, as well as a small clinical trial in children with autism in the next year

http://www.sciencedaily.com/releases/2013/03/130313182019.htm


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5 Comments

  1. Posted April 1, 2013 at 3:27 pm | Permalink

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  2. Posted May 6, 2016 at 5:28 am | Permalink

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  3. Posted June 4, 2016 at 11:30 am | Permalink

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  4. Posted June 5, 2016 at 3:57 am | Permalink

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